brain tumors in elderly

نویسندگان

afsoun seddighi functional neurosurgery research center, shohadatajrish hospital , shahid beheshti uninversity of medical sciences .

marjan vaezi functional neurosurgery research center,shohadatajrishhospital ,shahidbeheshtiuninversity of medical sciences .

shoeib naimian qazvin university of medical sciences

fatemeh yourdkhani shahidbeheshtiuninversity of medical sciences

چکیده

brain tumors in elderly are increasing as the number of people, who comprise the older population, does.about half of the patients with brain tumors appear to be over 60 years of age.in this review article, glioblastoma multiform, as the most common malignant tumor of the central nervous system in elderly is discussed in details of definition, prognosis, diagnosis, treatment and differential diagnosis. other tumors such as meningioma, pituitary adenoma, cns lymphoma and metastasis are also included to be reviewed.  treatment plans, either conservative or aggressive, classic or novel, approved or under investigation, are presented. furthermore different attitudes of treatment in the past and recently are also argued. conventional therapy, surgery, radiotherapy, chemotherapy radioimmunotherapy, hormonal therapy and some other novel methods of treatments are discussed in details for the glioma. determining factors which may be associated to the patient's response to each treatment planare also discussed. finally, some age related issues are provided to be paid attention to consider an old patient with brain tumor, and planning an optimal treatment in order to make the best management decisions.until recently,  peoplewith brain tumors in elderly, were used to be treated in conservative plans and often were excluded of the clinical trials but now the number of patients who desire and receive more aggressive therapy for brain tumors is increasing.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Pituitary tumors in the elderly.

The proportion of elderly subjects is growing in Western countries and, as a consequence, several diseases are now recognized with increasing frequency in the older segment of the population. Pituitary tumors are no exception to the rule. However, the presentation, diagnosis and management of pituitary tumors in the elderly, defined as patients older than 65 or 70 years depending on the differe...

متن کامل

Types of glioma brain tumors and genetic alterations in signaling pathways in them

Types of glioma brain tumors and genetic alterations in signaling pathways in them Background & Objective: Glioma is a common type of primary brain tumor originating in the glial cells that surrounds and supports neurons in the brain. These tumors arise from three different types of cells that are normally found in the brain: astrocytes, oligodendrocytes, and ependymal cells, accordingly types ...

متن کامل

CT-guided laser probe for ablation of brain tumors

In this study, 22 patients (15-75 years old) were selected and transferred to CT scan for tumor ablation. For ablations, after prep and drep under the local anesthesia and mild sedation in proper position, small incision made and special needle inserted and guided by proper direction to the core of the tumor. Then, laser probe inserted through the needle and laser energy delivered. Although we ...

متن کامل

Familiality in brain tumors.

BACKGROUND Familiality in brain tumors is not definitively substantiated. METHODS We used the Utah Population Data Base (UPDB), a genealogy representing the Utah pioneers and their descendants, record-linked to statewide cancer records, to describe the familial nature of primary brain cancer. We examined the familial clustering of primary brain tumors, including subgroups defined by histologi...

متن کامل

Irinotecan in Brain Tumors

Received April 12, 2002; accepted January 24, 2003. Irinotecan is a water-soluble derivative of camptothecin, an alkylator originally extracted from the Chinese tree Camptotheca acuminata. Laboratory studies have demonstrated the activity of irinotecan in a broad panel of pediatric and adult central nervous system tumor xenografts in athymic nude mice. These studies led to a Phase II trial that...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید


عنوان ژورنال:
international clinical neurosciences journal

جلد ۲، شماره ۲، صفحات ۵۵-۶۵

کلمات کلیدی

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023